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Hirudin can inhibit the activity of coagulation factor Xa, thereby reducing blood viscosity and improving blood circulation. In patients with rheumatic diseases, the blood often exhibits a hypercoagulable state, which may lead to poor local blood circulation in the joints, causing swelling and pain. The anticoagulant effect of hirudin helps alleviate this condition, thus relieving rheumatic symptoms.

2024

The mechanism by which hirudin acts on thrombin

Hirudin is the most prominent and extensively studied active component among the various bioactive substances extracted from leeches and their salivary glands. It is a small-molecule polypeptide composed of 65 to 66 amino acids. Leeches are rich in hirudin, which exhibits an exceptionally potent inhibitory effect on thrombin—making it the strongest naturally occurring, thrombin-specific inhibitor discovered to date. Hirudin possesses remarkable anticoagulant and antithrombotic activities, holding great promise for clinical applications in the treatment and prevention of various types of thrombosis.

2024

The process of cardiovascular and cerebrovascular blockage?

Atherosclerosis is one of the primary causes of cardiovascular and cerebrovascular blockages. It refers to lesions characterized by lipid deposition beneath the arterial intima, proliferation of smooth muscle cells and collagen fibers, accompanied by necrosis and calcification. Ultimately, these changes lead to thickening and hardening of the arterial walls and narrowing of the vascular lumen.

2024

How does hirudin enhance human immunity?

Hirudin is the most prominent and extensively studied active ingredient found in leeches and their salivary glands. It consists of 65 to 66 amino acids and exhibits potent anticoagulant and antithrombotic activities. Not only does it bind to free thrombin in plasma, but it also neutralizes thrombin that has already bound to fibrin, demonstrating exceptional anticoagulant efficacy.

2024

Cerebral thrombosis

A cerebral thrombus is a blood clot that forms when the blood's cellular components adhere to the inner lining of an artery, under conditions of slow blood flow and low blood pressure, on the basis of cerebral atherosclerosis and plaque formation. Clinically, it primarily manifests as hemiplegia. It commonly occurs after the age of 50, with a slightly higher incidence in men than in women.

2024

How does hirudin promote skin rejuvenation?

The application of hirudin in the beauty industry—particularly its ability to promote skin rejuvenation—is primarily attributable to its unique biological activity and multiple beneficial effects.

2024

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